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Trivia Duterte says to end VFA if US 'can't deliver at least 20 million doses' of vaccine

MANILA, Philippines — President Rodrigo Duterte on Saturday night threatened to go through with ending the Visiting Forces Agreement with the United States if it fails to deliver millions of doses of US-made COVID-19 vaccine.
The president's latest pronouncement follows the supposed botched negotiations with the US drugmaker Pfizer for 10 million doses and as his administration faces criticism of lagging behind in the global race to secure doses

US firms Moderna Therapeutics and Arcturus Therapeutics are ready to supply four to 25 million doses of their vaccines beginning the third quarter of next year should the government find their proposals acceptable, Philippine Ambassador to the US Jose Manuel Romualdez said in a statement earlier this month.

"If they can't deliver at least 20 million doses at a minimum, they better get out," Duterte said in English during his televised meeting with the coronavirus task force. "No vaccine, no stay here.

Duterte, who has not had a warm relations with Washington largely due to his drug war, You do not have permission to view the full content of this post. Log in or register now.the decades-old VFA in early February after the US reportedly cancelled the visa of Sen. Bato dela Rosa over his role in the government's "war on drugs".

The VFA, which governs the status and treatment of US soldiers in the Philippines and allows them to hold military exercises and provide technical assistance to security personnel, has been criticized in the past for allowing foreign troops in the country and for keeping the Philippines dependent on the US.

Duterte suspended the termination of the VFA in June "in light of political and other developments in the region" and, in November, extended the suspension for another six months.

The Philippines has so far secured only 2.6 million doses from AstraZeneca as a donation from the private sector, and the administration has yet to sign deals with drugmakers with only a few days before the year ends.

Officials have since denied that the country was late into talks for securing doses, even with Duterte only approving advanced payments in November after shunning the move which he said was the West making profit for the vaccines.

Its move to procure 25 million doses of China's Sinovac has also been widely criticized because the vaccine is more expensive and has a lower efficacy rate of 50%.

"Do not believe s*** about America delivering immediately," Duterte said. "If America wants to help, you deliver. Stop talking, what we need is the vaccine. Not your verbose speeches."

The administration is looking to inoculate 24.7 million Filipinos in 2021, with Sinovac seen to arrive the earliest by March, and AstraZeneca by the second quarter.

Over a million individuals in the US have already been inoculated after the Food and Drug Administration there issued emergency use approvals to Pfizer and Moderna. By mid-December, aYou do not have permission to view the full content of this post. Log in or register now. also reported that there are now 11.6 billion doses reserved even before a vaccine is put out in the market.

Indonesia, which has the highest number of infections in Southeast Asia, has so far secured 335.5 million doses, according to the report.

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Gusto rin tayong matulad sa dengvaxia. Yung isang nurse na tinurukan after 17 minutes namatay.
Kahit malayo sa content ng thread po ay papaliwanagan kita.

Ang Dengvaxia (CYD-TDV) po ay nasa "WHO List of Essential Medicines" magpa-hanggang ngayon. Dumaan po yan sa Phase 1, 2, 3 vaccine clinical trials bago i-approve and further revisions kalaunan ng nabisto yung sumikat na "contra-indication" niya --->. Kaya ang paalala ng WHO (officially last Dec. 13, 2017), "Dengvaxia, prevents disease in the majority of vaccine recipients but it should not be administered to people who have not previously been infected with dengue virus. Those not previously infected are at increased risk for severe dengue disease when vaccinated and subsequently infected with dengue virus."...na implied dito:
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Sa baba noong una, naghugas-kamay sila ayon sa kanilang nakaraang press release noong July 2016, sa kanilang posisyon sa dengvaxia: You do not have permission to view the full content of this post. Log in or register now.

Maliwanag naman yung last paragraph dyan:
Important research and implementation questions remain for CYD-TDV. Research on reduced or shorter interval dosing schedules and safety in *******t women are high priorities. An approach to evaluate epidemiologic data based on high-quality age-stratified surveillance is needed to infer likely seroprevalence by age in order to target vaccination efforts where seroprevalence data are not available. As the vaccine is introduced in endemic countries, determination of vaccine effectiveness by dose and duration of protection and long-term impact of vaccine programmes will be research priorities. However, it should be noted that using surveillance data to monitor population impact of a vaccination programme may be challenging as the year-to-year variability in dengue virus transmission may be greater than the expected vaccine impact on dengue illness. Special studies should be conducted to monitor the occurrence over time of severe dengue illness in vaccinated persons, particularly among vaccinated seronegative persons.
This document also supports the one above:
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Kaya di pa malinaw sa kanila at sa lahat yung precaution sa mga seronegative patients noon. Though duda na sila sa issue na yan, malaki pa rin ang kanilang tiwala dyan sa efficacy ng first "approved" dengue vaccine! Patuloy na babantayan lang yung resulta ng pagbabakuna para maliwanagan sa kanilang pag-alala.....

Ito po yung immunization implementation sa ngayon ayon sa WHO:

World health organization position evolution​

The WHO has issued two position papers on Dengvaxia®, one based on the data used for initial licensure and the second addressing modifications to the initial indication based on the observed safety signal in seronegative vaccine recipients in all ages studied. The first position was issued in July 2016 and contained the following observations and recommendations:

  1. CYD-TDV should only be introduced in geographic settings where epidemiological data indicate a high burden of disease (seroprevalence 70% or greater in the age group targeted for vaccination);
  2. The vaccine is not recommended when seroprevalence is below 50% in the age group targeted for vaccination;
  3. Use of CYD-TDV in populations where seroprevalence is low in the age group considered for vaccination is not recommended;
  4. If CYD-TDV is introduced, it should be administered as a 3-dose series given on a 0/6/12-month schedule;
  5. Because of the association of CYD-TDV with increased risk of hospitalized and severe dengue illness in the 2–5-year age group, CYD-TDV is not recommended for use in children under 9 years of age;
  6. CYD-TDV has not been studied as an intervention for dengue outbreak control and is not expected to have a significant impact on the course of the ongoing outbreak; and
  7. Long-term monitoring for severe dengue, in particular in seronegative vaccinated subjects, should be done in selected areas.


Based on WHO’s recommendation #7 and the increasing evidence of a detrimental effect of vaccination in seronegative individuals, the Sponsor embarked on exploring the effect of age and serostatus on vaccine efficacy and long-term safety (described earlier). Based on the data, the Sponsor requested a change in the vaccine’s label:

Based on up to six years of clinical data … For those not previously infected by dengue virus, however, the analysis found that in the longer term, more cases of severe disease could occur following vaccination upon a subsequent dengue infection … Based on the new analysis, Sanofi will propose that national regulatory agencies update the prescribing information … For individuals who have not been previously infected by dengue virus, vaccination should not be recommended. November 29, 2017


(You do not have permission to view the full content of this post. Log in or register now., accessed 7 MAY 2019)

The WHO revised their position based on this new information in September 2018:

  1. CYD-TDV has been shown in clinical trials to be efficacious and safe in seropositive individuals, but carries an increased risk of severe dengue in those who experience their first natural dengue infection after vaccination (seronegative individuals);
  2. Only people with evidence of a past dengue infection should be vaccinated based on an antibody test, or on a documented laboratory confirmed dengue infection in the past. If pre-vaccination screening is not feasible, vaccination without individual screening could be considered in areas with recent documentation of seroprevalence rates of at least 80% by age 9 years;
  3. Screening tests would need to be highly specific to avoid vaccinating truly seronegative persons and to have high sensitivity to ensure that a high proportion of seropositive persons are vaccinated;
  4. Decisions about implementing a pre-vaccination screening strategy with the currently available tests will require careful assessment at the country level, including consideration of the sensitivity and specificity of available tests;
  5. The vaccine should be used within the indicated age range, which in most countries is 9–45 years. The age group to target for vaccination depends on the dengue transmission intensity in a given country;
  6. In travelers who have already had a documented dengue illness or are seropositive, vaccination before travel to high dengue transmission settings could be considered; and
  7. There is an urgent need for the development of highly specific and sensitive rapid diagnostic tests (RDTs) for determination of dengue serostatus.
Ito naman yung latest drug information as approved by the US FDA last 2019: You do not have permission to view the full content of this post. Log in or register now.
Mas malinaw po itong sundin. Pero kung duda pa rin tayo sa bakuna, stick na lang tayo sa basic treatment and preventive procedure na ayon dito at nakagawian - paracetamol at kulambo he he:
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1997 pa yang dengue vaccine na nadiskubre ng Saint Louis University Research, bago binili ang rights ng Acambis Inc (pharmaceutical). Nalipat yan sa Sanofi Pasteur noong 2008 at na-approve noong 2015. Noong December 2015, aprobado yan ni PNOY, di po ba? Mexico was the first country to approve and try dengvaxia....The rest of the world followed. Sa atin nagkaproblema, bakit?

Kung i-review nating maigi yung timeline ng dengvaxia, ay makikita natin yung pagkakamali ng bawat concerned individuals and groups (mula WHO, Sanofi, medical groups, our gov't officials, media, atbp.). Kapag pinagsama yung tama at mali, sa perwisyo nauuwi. Check nyo dito.
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(Yung mga balitang namatay dahil sa dengvaxia ay walang matibay na ebidensiya po. Kahit saang sulok ng mundo ay di yan tinanggap ng scientific/medical community. )

Sometimes, we need ample time and data to reveal the real truth. But in the end, we still can't please everyone because media always create controversies, and we're falling from it.

Bantayan ninyo ang media....gagawin din yan sa COVID-19 vaccines kalaunan!

Sana po ay naliwanagan kayo sa istorya ng dengvaxia sa ating bansa, at maging maingat sa pagsusuri. Sorry for the long narration. It's just me he he. (Kung may mali po ako, ipaliwanag na lang po ninyo.)
 
You will never get it if you still pretend na neutral ka, sa mga comments mo clearly galit kalang sa mga asal nang mga DDS. Relax lang paps, baka magaya ka na dito ke Anwahe, na na inlove na ke Comrade Rodrigo.

Ako nga na palagi na-bully dito noon dahil neutral ako at critize ko si PDUTS, but it never made me hate them. Ngaun medyu tame na mga pro-Duterte dito, dahil syempre unti-unti na sila tumatalino sa politics.
 
[XX='Delta India Charlie Kilo, c: 623884, m: 262490'][/XX] di naman sa ganun na galit, point out ko lang naman kung ano yung nasa isip ko na kasalanan nila. wala naman akong real hate sa kanila, unless di na sila nag aargumento at insulto na lang.
(mahirap talaga pag type lang yung pinagsasabi ko, di mo malalaman yung tono ko.)

ngayon lang talaga ako naging active critic sa pulitika, di naman talaga neutral yung pinagsasabi ko.
medyo tame na talaga, di na naging active yung iba.
 
[XX='Ooooooooo, c: 618769, m: 1757659'][/XX] So, ano po gusto nyong mangyare? Hayaan nalang kayong mag -rally kasi di naman effective ang pananakot ng presidente, ganun?
 
Tama ka bro. By this time, kilala na dapat ng tao yung profile nya whether you're with him or against him. He is what he is eka nga. There's a good and bad side in him, but he's not the likeable type because he's not a good speaker, but he knows himself much. DU30 uses the power of media when he wants something or want to send a message. His spokesman H "Bad Piggie" R cleans his tracks. (Maglaro ka ulit ng Angry Birds he he.)
Kung iba yung nakaupo, tanggal na dapat si Duke dahil naka-ilang strikes na nga. Kahit saan lumagay na departamento malas! So, it's normal practice to fire and replace him, pero may "hidden bond" yung dalawa. Si Duke yata, ayaw din mag-resign he he. That's for them to decide.
Duterte has his ups and downs. Sira lang siya sa pagpili ng taong tutulong sa kanya - in my opinion. At ngayon, di na uubra yung style nya dahil wala siyang full resources to control/solve his problem like he used to. He's bold in using an old, risky poltical strategy to push the US to help him using "VFA". I don't like as it sounds like an insult, but it also sends a message to the US - "You help me. I help you!". "VFA" is more US power in the Pacific. The US needs it. Yes it's a risk, but Presidents take risks most of the time.
 
Actually importante sa kanila ang VFA because of territorial power. Kung gusto kong magmukhang malakas sa kalaban niyang China, gagawa ako ng paraan para makakuha ng lakas doon sa mga kalapit na bansa na siyang magpapakita na hawak namin itongugar na ito. Kung walang VFA, iiyak ang mga Amerikano. Note that ang Philippines ay isang strategic location na kung saan di na-uutilize ng bansa natin due to low budget and focus. Kung mapaglalaruan natin a n g territorial waters natin, mas malakas pa tayo sa ibang bansa kung iisipin. Sadyang kulang lang tayo ng guts at utak. In China, the only asset that they have is full of artillery and equipements to spark the war. Ang habol naman natin sa VFA ay training kung paano lumaban sa intense war sa mga kabundukan at mga tactics kung paano masusurvive ang labanan sa ganung sitwasyon. This is in preparation sa pagpapapbagsak sa mga NPA sa mga kabundukan kaya kung mapapansin niyo ay kumukonti na ang tropa at madaminng tumitiwalag. (Pasensiya na agad sa mga CPP-NPA na nandito sa PHC) It is a win-win situation kapag sa VFA, pero kung mawawala man ang VFA, ang may malaking kawalan ay US kaya ayaw na ayaw nilang bitawan ito.
 
Actually, lahat ng vaccines ay delikado. Kanya-kanyang startegy lang yan para makabenta at mamarket na mas effective sa kanila. Puro paninira lang yan sa isa't-isa para lumamang ang isa. The fact that every country ay kailangan magfile ng emergency file to approve vaccines (di ko alam tawag dun) ay napaka-risky. Kahit na sabihin pa natin na 99% effficacy rating niyan, di pa din tayo sure sa ganyan. Ang pagggawa ng isang vaccine ay umaabot ng napakahabang proseso, you wilk need 10 years to prove your work. Kapag okay sa loob ng 10 years, masasabi na natin na mabisa talaga ito. Nakakatakot lang dahil nafforce tayo na bumili at gumawa ng vaccine ng mabilis, pero di natin malalaman kung anong magiging epekto nito after how many years pagkatapos kang bakunahan. Mapa-Chinese vacvine, american vaccine mula sa sikat na pharmaceutical company pa yan ay parehas lang niyang gusto ay pera. Wala yan silamg pake sa humanity, the only thing in their mind is to make money kaya kung mapapansin niyo sa loob, (sabe ng prof namin) sila din ang gumagawa ng mga sakit at viruses na yan para makakuha ng advantage. Yan ang nakakatakot sa mundo ngayon. Ang tanging magagawa lang natij para maiwasan at malabanan ang virus na ito at STAY AT HOME, KEEP SAFE, CLEAN, COVER. Prevention is better than cure nga kaya kung pwede huwag muna tayong mag-gala gala at tiisin muna natin ang ating mga kati dahil para sa atin din ito. Kung matitiis natin ito, sa mga susunod na buwan o taon ay makakaalis na tayo ng freely na walang inaalala mula sa labas.
 
Yan denvaxia ay kurapsyon ni drilon at angara noon, pati ni panot, pinayagan iturok sa mga bata eh nasa phase 3 palang ang pag aaral niyan noon, si drilon pinapasara ang forensic lab, na nag iimbestiga sa mga naturukan ng dengvaxia
 
Mahirap maging Presidente at maging Leader ng maraming tao. Kahit Anong Move o Desisyong gawin meron pa din Kritiko sa paligid. Yun yung Opinyon nila na sa tingin nila ay tama o makakabuti sa mamamayan.
 
He he. Yung nakaupo ngayon - si RED. Si Department of Heath Undersecretary Dr. Rolando Enrique Domingo yan, pero di ko alam yung mga pangalan ng UP-PGH Dengue Investigative Task Force. That was their initial findings back then, but no further medical study supports their claim, except what they said. Kaya puro "maybe" ang maririnig mo sa kanilang sinabi. Sa medical field o kahit ano pang larangan, dapat may substantial studies/facts/evidence, hindi lang sabi-sabi using preliminary data. Napatunayan na rin yang accusation na mali vs. Sanofi kaya nga naging approved drug yan sa US and Europe, atbp. Sanofi still is to be blamed, since their "relabeling" issue caused the wrong protocols to be followed in the Philippines before it was known, so they have to pay for the damages - klaro yan. But still dengvaxia remains an officially approved dengue vaccine, whether we like it or not.

Maaring yung intention nila noon is to pin the wrong implementation of the drug causing harm to the patients based on the proper protocol of its application or just create a controversy as what happened. It was just a wrong hypothesis by UP-PGH. Kaya mahirap pagtiwalaan din sila kahit tinatawag na mga experts in their field because they lack the highest level of knowledge before opening their mouths, especially in high-profile forensics. Malalaman lang natin yung kakayahan ng mga ganitong mga eksperto sa tagal ng kanilang serbisyo - pero huli na ang lahat.
...Kaya kahit sa medical field, may politika rin he he. Kahit saang industriya meron nyan, sa gobyerno pa. Kaya dapat, well informed tayo sa buod ng pinag-uusapan, hindi yung galing lamang sa sinasabi ng iba. That's where we are divided in the understanding, di po ba?
 
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Maganda sana, pero hindi bat ang Pfizer ay private company paano mauutusan ng US ang through threat? Gayong paunahan ang pagorder ng bakuna? So VFA and vaccine is well, unreal for now.
 
Happy New Year T.S (and everybody, included dds! 😇)
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