Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response. Proteins responsible for detecting stimuli are generally termed receptors, although in some cases the term sensor is used. The changes elicited by ligand binding (or signal sensing) in a receptor give rise to a biochemical cascade, which is a chain of biochemical events known as a signaling pathway.
When signaling pathways interact with one another they form networks, which allow cellular responses to be coordinated, often by combinatorial signaling events. At the molecular level, such responses include changes in the transcription or translation of genes, and post-translational and conformational changes in proteins, as well as changes in their location. These molecular events are the basic mechanisms controlling cell growth, proliferation, metabolism and many other processes. In multicellular organisms, signal transduction pathways regulate cell communication in a wide variety of ways.
Each component (or node) of a signaling pathway is classified according to the role it plays with respect to the initial stimulus. Ligands are termed first messengers, while receptors are the signal transducers, which then activate primary effectors. Such effectors are typically proteins and are often linked to second messengers, which can activate secondary effectors, and so on. Depending on the efficiency of the nodes, a signal can be amplified (a concept known as signal gain), so that one signaling molecule can generate a response involving hundreds to millions of molecules. As with other signals, the transduction of biological signals is characterised by delay, noise, signal feedback and feedforward and interference, which can range from negligible to pathological. With the advent of computational biology, the analysis of signaling pathways and networks has become an essential tool to understand cellular functions and disease, including signaling rewiring mechanisms underlying responses to acquired drug resistance.
Sorry kung mahaba. Pero pakibasa na lang po in case man na may ginawa akong mali.
Naka smart bro unli data 599 ako sa Globe at Home modem. Super bilis naman ng internet. Most of the time siguro mga nasa 40mbps siya. Kaso after nung bagyo netong October, nag loko yung Band 41 dito samin sa Bay...
Hello po! Ano po kaya magandang antenna para sa isang modem ZTE MF286RA na nasa 4th floor, no balcony nor windows (closed environment), low signal (due to the building siguro) pero super lapit sa cell tower?
Sabi po nila dapat daw po walang obstructions yung mga outdoor antenna like mimo...
May iba pa ba sa inyo naka experience na hanggang H+ lang signal ngayon? Hindi na nag 4g signal ko simula 3pm. Sinubukan ko gumamit ng ibang apn ganun pa rin... any suggestions po?
Hi po,
Medyo mahirap yung signal dito sa loob ng bahay, zero bars talaga kahit anong network kaya nilalagay ko yung phone sa bintana magka signal lang.
May way kaya para lumakas signal dito sa loob?
Thanks po.
According to internet testing leader Ookla, Globe's mobile services continue to improve due to its sustained aggressive network rollout of 4G LTE and 5G in more areas across the country.
File photo: Globe 5G speed test in BGC
Better consistency score than ever!
Ookla's Q1...
Pa help po, nawalan po ako ng signal sa Smart prepaid ko, kanina lang umaga naka service disabled na. Di ko alam anong nangyare may promo pa naman yun na 2 gigagame99. ๐
Mga paps kung mhina signal nyo ito na ang sagot try nyoto mga paps
click nyo ung activated or keep Alive pra gumana mga paps so hito na mga paps
๐
https://dropmb.com/download/b4baf392707373b107bf2dea90bc2b1b.html
Like lang paps ok na skin un...
Patulong naman mga sir, block na ba ko sa smart? Nanonood lang kase ako Kimetsu no yaiba sa fb with injector to tas biglang nawala signal ko sa smart tas pagbalik biglang 3g na sya pati yung tabi ng battery percent ko wala na ring lumalabas na 4g. Sa area ko lang ba to? kahit i airplane mode on...
anyone experiencing network signal ?
ayaw mag 4G ng network ko mula pa kaninnag umaga.. kagabi okay pa naman.. ngayon 3G lang tapos pawala-wala pa.. location ko pasig area..
Guys, any info kung bakit bigla na lang hindi gumagana mobile data ko . LTE covered naman are namin saka malakas signal. Pag sinwitch ko sa globe gumana pero sa TNT kahit E signal wala.
P.S LTE upgraded sim po yung gamit ko
Pano ba magging full bar signal ng 936 ko, may anthena naman ako, pero 3 bar lang tlaga naka pwesto sya sa kwarto ko , tpus antena nasa 3rd floor lampas sa bubong ung antenna,
Need ko paba itaas ng sobra ung antenna ko?
at yung wifi modem ko mas ok ba kahit nalagay yung anthenna ipwesto ko sa...