Pentasomy X, also known as 49,XXXXX, is a chromosomal disorder in which a female has five, rather than two, copies of the X chromosome. Pentasomy X is associated with short stature, intellectual disability, characteristic facial features, heart defects, skeletal anomalies, and pubertal and reproductive abnormalities. The condition is exceptionally rare, with an estimated prevalence between 1 in 85,000 and 1 in 250,000.
The condition has a large variety of symptoms, and it is difficult to paint a conclusive portrait of its phenotypes. Though significant disability is characteristic, there are so few diagnosed cases that confident conclusions about the presentation and prognosis remain impossible. Pentasomy X may be mistaken for more common chromosomal disorders, such as Down syndrome or Turner syndrome, before a conclusive diagnosis is reached.
Pentasomy X is not inherited, but rather occurs via nondisjunction, a random event in gamete development. In rare cases, it may be related to a parent's chromosomal mosaicism. The karyotype observed in pentasomy X is formally known as 49,XXXXX, which represents the 49 chromosomes observed in the disorder as compared to the 46 in normal human development.
mga master, lodi qng petmalu..
may free load daw.. Gs50 send to 8080 or 8888 20x.. confirm ko lng po if totoo ito?
may nag post kasi sa fb na totoo daw..
wag naman po kayo magagalit o mang bash.. nagtatanong lng ako..
#respect
mga master, lodi wng petmalu.. pwede po ba ma share yung Data mo? sa ibang phone number.. like share a load or pasaload pero Data ung ipapasa mo.. How po?
thanks sasagot!