Closed Taiwan Scientists Find Antibody That Fights COVID19

TAIPEI (Taiwan News) — A team of scientists at Taiwan's Chang Gung University (CGU) has found a monoclonal antibody (mAb) that can inhibit the Wuhan coronavirus (COVID-19) by over 90 percent.

The team spent several months searching for the antibody, which has the ability to inhibit the virus by 90 to 98 percent. In addition, it has been found to be effective against all four main virus strains.

In early April, researchers from CGU and Academia Sinica, the National Defense Medical Center, and Oxford University You do not have permission to view the full content of this post. Log in or register now. that they had identified 25 strains of mAbs in three patients infected with COVID-19. At the time, they had already identified one of which could potentially inhibit the virus from entering the body, paving the way for medication.
Shih Shin-ru (施信如), director of the CGU Research Center for Emerging Viral Infections confirmed on Thursday (May 28) that through experiments there the antibody has the ability to block the virus from entering the human body, with the ability to inhibit the virus ranging between 90 to 98 percent, reported You do not have permission to view the full content of this post. Log in or register now.. Moreover, the antibody had the same neutralization effect on the Wuhan, American, European, and Egyptian strains of COVID-19, making it an ideal candidate for therapeutic drugs.
Shih said that unlike pharmaceuticals, which can be toxic and produce side effects, antibodies are made from substances that naturally occur in the human body. Therefore, they are not only safe but also highly specialized, enabling them to identify specific viruses and inhibit or eliminate them and will not affect normal healthy cells in the process, while reducing the occurrence of side effects.

The director added that now that the CGU team has identified a suitable mAb, they will start a technology transfer to the private sector in June, carry out further tests, and ramp-up to mass production. If all goes well, the antibody could be commercially available by as soon as the end of the year, said Shih.


By You do not have permission to view the full content of this post. Log in or register now., Taiwan News, Staff Writer
2020/05/28 15:23

 

[Safety1st]

When a disease is new, there is no vaccine until one is developed. It can take a number of years for a new vaccine to be developed, yung mga sakit nga gaya malaria and H.I.V., utterly frustrate scientists to this day, despite astonishing new weapons like gene-editing, until now wala pa din mga vaccine sa mga nabanggit na yan.

 

[Carys]

When a disease is new, there is no vaccine until one is developed. It can take a number of years for a new vaccine to be developed, yung mga sakit nga gaya malaria and H.I.V., utterly frustrate scientists to this day, despite astonishing new weapons like gene-editing, until now wala pa din mga vaccine sa mga nabanggit na yan.

Look what Taiwan did and you'll know the difference. Vaccines are very vague to say it's an antiviral medicine or whatnot, they went further to develope a monoclonal antibody not just a vague vaccine.

 

[benriee]

good news yan. sana all ok maging results ng mga test para ma mass produce na. need na ng world yan

 

[Carys]

good news yan. sana all ok maging results ng mga test para ma mass produce na. need na ng world yan

Kaya nga, let's hope for the good things! Helping spread positivity is much wiser than antagonising.

 

[benriee]

tama para lahat mabuhayan ng loob kesa nagmumukmok nalang na hopeless

 

[Carys]

https://www.YøùTùbé.com/watch?v=SB2Dr0_rX3Y

Worth the time to watch this, sir.

 

[benriee]

@Carys..watch ko later thank you

 

[Graphmaster]

INTRAVENOUS MICRONUTRIENT INFUSIONS
therapy

 

[Safety1st]

Look what Taiwan did and you'll know the difference. Vaccines are very vague to say it's an antiviral medicine or whatnot, they went further to develope a monoclonal antibody not just a vague vaccine.

Once a viable vaccine without detrimental side effects is developed based on animal-model research, it is time for stage three: clinical development. Usually, this stage requires some sort of government approval, since it involves testing the vaccine on humans. After the approval has been granted, three trial phases of human testing take place, each broader than the previous. The aim is to determine the safety and effectiveness of the vaccine, as well as other important information, such as dosage, immunization schedule, rare side effects, etc. Once a vaccine passes all three trials, it has to be approved by a government organization. In the U.S. that would be the Food and Drug Administration, whose Center for Biologics Evaluation and Research (CBER) is responsible for regulating vaccines.

Which method/approach will prove the most successful in eradicating the new coronavirus remains to be seen, but one thing is certain: Global pharma is on high alert, and the clock is ticking.

WAG Paniwalaan agad agad ang napapanuod o nababasa nyo! Even yung mga nai sensationalized article/video

 

[Carys]

Once a viable vaccine without detrimental side effects is developed based on animal-model research, it is time for stage three: clinical development. Usually, this stage requires some sort of government approval, since it involves testing the vaccine on humans. After the approval has been granted, three trial phases of human testing take place, each broader than the previous. The aim is to determine the safety and effectiveness of the vaccine, as well as other important information, such as dosage, immunization schedule, rare side effects, etc. Once a vaccine passes all three trials, it has to be approved by a government organization. In the U.S. that would be the Food and Drug Administration, whose Center for Biologics Evaluation and Research (CBER) is responsible for regulating vaccines.

Which method/approach will prove the most successful in eradicating the new coronavirus remains to be seen, but one thing is certain: Global pharma is on high alert, and the clock is ticking.

WAG Paniwalaan agad agad ang napapanuod o nababasa nyo! Even yung mga nai sensationalized article/video

Is this your own statement or based from nababasa mo or even sensationalised article? Just saying

 

[Carys]

Once a viable vaccine without detrimental side effects is developed based on animal-model research, it is time for stage three: clinical development. Usually, this stage requires some sort of government approval, since it involves testing the vaccine on humans. After the approval has been granted, three trial phases of human testing take place, each broader than the previous. The aim is to determine the safety and effectiveness of the vaccine, as well as other important information, such as dosage, immunization schedule, rare side effects, etc. Once a vaccine passes all three trials, it has to be approved by a government organization. In the U.S. that would be the Food and Drug Administration, whose Center for Biologics Evaluation and Research (CBER) is responsible for regulating vaccines.

Which method/approach will prove the most successful in eradicating the new coronavirus remains to be seen, but one thing is certain: Global pharma is on high alert, and the clock is ticking.

WAG Paniwalaan agad agad ang napapanuod o nababasa nyo! Even yung mga nai sensationalized article/video

Oh para may listahan ka din sir of some of our intel reports last April, wishing they are sensational , as part of my job in AU intelligence unit:

1) How Monoclonal Antibodies Might Prove Useful Against The Coronavirus
March 26, 2020
You do not have permission to view the full content of this post. Log in or register now.
" One such project, supported by the Defense Advanced Research Projects Agency, is called the Pandemic Prevention Platform. The idea is to shorten to just 90 days the time it takes to develop effective countermeasures to a biological threat like the coronavirus. "


2) Researchers developing potential coronavirus antibody therapies
Dr. Jeff Balser, President and CEO of VUMC, discusses progress on research for antibody-based COVID-19 therapies.
March 23, 2020
You do not have permission to view the full content of this post. Log in or register now.

"Vanderbilt’s many academic partners in the effort to identify and validate anti-SARS-CoV2 human antibodies include:

Helen Chu, MD, MPH, assistant professor of Medicine and infectious disease expert at University of Washington School of Medicine in Seattle;
Michael Diamond, MD, PhD, an internationally known expert on emerging infectious diseases at Washington University School of Medicine in St. Louis;
Frances Eun-Hyung Lee, MD, director of the Asthma, Allergy, and Immunology Program at Emory University School of Medicine in Atlanta;
Ralph Baric, PhD, professor of Epidemiology at the University of North Carolina School of Medicine at Chapel Hill; and
Dan Barouch, MD, PhD, director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center in Boston."


3) Monoclonal Antibodies Could Help Fight Against Coronavirus
Apr 23, 2020
William A. Haseltine
Healthcare Contributor
You do not have permission to view the full content of this post. Log in or register now.
"How soon will drugs be available? My guess, within three to four months for the first approvals.

-It may take several weeks to demonstrate effectiveness in animals.
-Human safety studies can be done with no more than 30 people in about a month. These drugs are generally known to be safe though more testing for safety will be required.
-Tests of the drugs’ effect in reducing the viral load in infected patients should take no longer than a month.
-Most time consuming will be large scale manufacturing of the drugs, once approved."

"The work was completed by a team of scientists working in four different cities from across the length and breadth of China. While still in its early phases, the discovery is significant. There has been much talk in recent weeks about the use of convalescent serum and hyperimmune globulins—essentially, collecting blood from patients who have recovered from COVID-19 and giving the plasma to people who are sick. This discovery offers us the hope of a purer and potentially safer form of this type of treatment."


4) Harnessing internal expertise and via new collaborations, the aim is to identify monoclonal antibodies that have the potential to recognise, bind to and neutralise the SARS-CoV-2 virus, to decrease the impact of COVID-19.
April 8, 2020
You do not have permission to view the full content of this post. Log in or register now.
"More than 50 virology, protein engineering, clinical and bioprocess experts across BioPharmaceuticals R&D and Operations are working on this effort, using proprietary antibody discovery technology that was previously developed under an agreement with the US Defense Advanced Research Projects Agency (DARPA) as part of the Pandemic Preparedness Platform programme. As part of the DARPA programme, the technology enabled AstraZeneca scientists to rapidly discover potential therapeutic antibodies for influenza-A in less than 60 days."

 

[Safety1st]

Oh para may listahan ka din sir of some of our intel reports last April, wishing they are sensational , as part of my job in AU intelligence unit:

1) How Monoclonal Antibodies Might Prove Useful Against The Coronavirus
March 26, 2020
You do not have permission to view the full content of this post. Log in or register now.
" One such project, supported by the Defense Advanced Research Projects Agency, is called the Pandemic Prevention Platform. The idea is to shorten to just 90 days the time it takes to develop effective countermeasures to a biological threat like the coronavirus. "


2) Researchers developing potential coronavirus antibody therapies
Dr. Jeff Balser, President and CEO of VUMC, discusses progress on research for antibody-based COVID-19 therapies.
March 23, 2020
You do not have permission to view the full content of this post. Log in or register now.

"Vanderbilt’s many academic partners in the effort to identify and validate anti-SARS-CoV2 human antibodies include:

Helen Chu, MD, MPH, assistant professor of Medicine and infectious disease expert at University of Washington School of Medicine in Seattle;
Michael Diamond, MD, PhD, an internationally known expert on emerging infectious diseases at Washington University School of Medicine in St. Louis;
Frances Eun-Hyung Lee, MD, director of the Asthma, Allergy, and Immunology Program at Emory University School of Medicine in Atlanta;
Ralph Baric, PhD, professor of Epidemiology at the University of North Carolina School of Medicine at Chapel Hill; and
Dan Barouch, MD, PhD, director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center in Boston."


3) Monoclonal Antibodies Could Help Fight Against Coronavirus
Apr 23, 2020
William A. Haseltine
Healthcare Contributor
You do not have permission to view the full content of this post. Log in or register now.
"How soon will drugs be available? My guess, within three to four months for the first approvals.

-It may take several weeks to demonstrate effectiveness in animals.
-Human safety studies can be done with no more than 30 people in about a month. These drugs are generally known to be safe though more testing for safety will be required.
-Tests of the drugs’ effect in reducing the viral load in infected patients should take no longer than a month.
-Most time consuming will be large scale manufacturing of the drugs, once approved."

"The work was completed by a team of scientists working in four different cities from across the length and breadth of China. While still in its early phases, the discovery is significant. There has been much talk in recent weeks about the use of convalescent serum and hyperimmune globulins—essentially, collecting blood from patients who have recovered from COVID-19 and giving the plasma to people who are sick. This discovery offers us the hope of a purer and potentially safer form of this type of treatment."


4) Harnessing internal expertise and via new collaborations, the aim is to identify monoclonal antibodies that have the potential to recognise, bind to and neutralise the SARS-CoV-2 virus, to decrease the impact of COVID-19.
April 8, 2020
You do not have permission to view the full content of this post. Log in or register now.
"More than 50 virology, protein engineering, clinical and bioprocess experts across BioPharmaceuticals R&D and Operations are working on this effort, using proprietary antibody discovery technology that was previously developed under an agreement with the US Defense Advanced Research Projects Agency (DARPA) as part of the Pandemic Preparedness Platform programme. As part of the DARPA programme, the technology enabled AstraZeneca scientists to rapidly discover potential therapeutic antibodies for influenza-A in less than 60 days."

With all due respect po, ang punto ko po ay ito, Hindi basta basta makakagawa ng vaccine para sa Covid ng ganung kadali o kaigsing panahon, hindi mo pwedeng sabihin na tama na kaagad ang findings nyo base lamang sa mga nakalap nyo na information(s) (ikaw na mismo nagsabi diba na "AU intelligence unit") sya nga po pala, may Security at Secret intel ang AU, kung alin ka man dyan hindi ikaw ang dapat mag post ng mga nakalap nyo publicly

 

[Carys]

With all due respect po, ang punto ko po ay ito, Hindi basta basta makakagawa ng vaccine para sa Covid ng ganung kadali o kaigsing panahon, hindi mo pwedeng sabihin na tama na kaagad ang findings nyo base lamang sa mga nakalap nyo na information(s) (ikaw na mismo nagsabi diba na "AU intelligence unit") sya nga po pala, may Security at Secret intel ang AU, kung alin ka man dyan hindi ikaw ang dapat mag post ng mga nakalap nyo publicly

No, your point is misleading, you even quoted articles without proper credits. And there are lots of intelligence unit in AU, we are just one arm among the branches, no need to know, nevertheless, these infos are basically not important to us, these are even posted publicly months ago. So, no need to worry on your behalf.

Just don't post things without giving proper credit to whom it's due, next time.

Quoting "Hindi basta basta makakagawa ng vaccine para sa Covid ng ganung kadali o kaigsing panahon, hindi mo pwedeng sabihin na tama na kaagad ang findings nyo" Ngayon, alin sa pinost ko ang nagsasabi ng ganyan? Opinyon mo ba yan o base din yan sa pinaniniwalaan mo galing sa ibang claims na hindi mo binigyan ng credit?

Sya nga din po pala, my point is this, again, "Helping spread positivity is much wiser than antagonising them."

Cheers!

 

[Delta India Charlie Kilo]

Si Francis Leo Marcos yung nag fund nang research na yan, ayun sa ancient prophecy nang mga Ifugaos si FLM yung magiging heir nang old kingdom na once existed during the Pangaea super continent mga advance race of time traveling inter-dimensional beings.

 

[Carys]

Si Francis Leo Marcos yung nag fund nang research na yan, ayun sa ancient prophecy nang mga Ifugaos si FLM yung magiging heir nang old kingdom na once existed during the Pangaea super content mga advance race of time traveling inter-dimensional beings.

DMT, Shrooms, LSD, Salvia or MDMA? Want to trip there also.

 

[Delta India Charlie Kilo]

sleep deprivation, I don't do drugs.

 

[Arjheizl28]

kht sabihin mong panglaban nga yan sa covid eh panu ung my covid taz ky sakit pang iba like my sakit sa puso highblood.. pwd kya yan mapapatay nya ung virus at sabihin na ntin mabisa yan pero panu kung lalala nmn ung ibang sakit ng na infect sa covid at un ang cause ng paglamatay nila.. dahil ndi kinaya ng puso nila ung dosage ng gamot na yan kya wala dn bka good sa mga taong covid lng ang nararamdamang sakit..

 

[ramoeld]

sana maging successful para nmn balik normal na buhay natin