Option 1: Take the LRT2 Purple Line and go down at Recto Station. From here, transfer to Doroteo Jose Station of LRT 1 Yellow Line and ride an LRT bound for Baclaran. Get down at Central Station. Walk along Taft Ave passing by Manila City Hall, until you reach P. Burgos. The building at the corner is the National Museum.
Option 2: From Cubao, you can ride a jeepney/FX that is bound for Quiapo and asked to be dropped at Rizal Avenue. Ride an LRT 1 bound for Baclaran via Doroteo Jose Station.
Get down at Central Station. Walk along Taft Ave passing by Manila City Hall, until you reach P. Burgos. The building at the corner is the National Museum.